Activin Receptors

《英文msh词典》Activin Receptors
[主题词] Activin Receptors
[同义词] Activin Receptor-Like Kinases
[入口词] Activin Receptor
[入口词] Activin Receptor-like Kinase
[入口词] Receptor,Activin
[入口词] Activin Receptor like Kinase
[入口词] Activin Receptor like Kinases
[入口词] Kinase,Activin Receptor-like
[入口词] Kinases,Activin Receptor-like
[入口词] Receptor-like Kinase,Activin
[入口词] Receptor-like Kinases,Activin
[中文释义] 激活素受体
[英文释义] Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES,thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS,TRANSFORMING GROWTH FACTOR BETA),ALK's consist of two different but related protein kinases,Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS,TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS,TYPE I ) with subsequent activation of the type I kinase activity.